… the proangiogenic activation of VEGF receptors (VEGFRs) by VEGF family members in
skeletal muscle, we develop a computational model of VEGF isoforms (VEGF 121 , VEGF 165 ), …

… a computational model of the interactions between NRP1 and … complexes by the isoforms
VEGF 121 and VEGF 165 . We … computational models of endothelial cell behavior in in vitro …

… -specific phosphorylation in vivo, mediated by Neuropilin-1. These … -developed computational
models of VEGF distribution and … VEGF production by skeletal muscle; or degradation of …

… We previously developed a computational model for predicting … Interactions of VEGF isoforms
with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal …

… release regulate VEGF diffusion in vivo are therefore not yet … VEGF isoforms also differentially
bind to neuropilin-1 and -2 (… diffusion-based computational model of VEGF transport. The …

… results, a computational model of VEGF distribution in the … receptors VEGFR-1, VEGFR-2,
and co-receptor neuropilin-1. … human VEGFR-1 to the third Ig domain of human VEGFR-2 …

… co-receptor neuropilin-1 (NRP1), as well as sVEGFR1. The … computational models of the in
vivo biochemical interactions … entire 65 kg as homogenous skeletal muscle with a density of …

… Computational models of VEGF transport in vitro and in vivo … Neuropilin-1 is a VEGF 165
-specific coreceptor that enhances binding to VEGFR2. Using computational models of human …

… effects in vivo are currently unknown. We previously developed a computational model for
… and opposite effect in which increased VEGF occupancy of neuropilin-1 (NRP1) and the …

… bioavailability and interaction with the co-receptor Neuropilin-1. … both in vitro and in vivo
experimental evidence, VEGF xxx a … Computational modelling of systems pharmacology have …